[Effect of jinshui-liujun decoction on chronic bronchitis in rats]

Zhong Yao Cai. 2002 Jul;25(7):484-6.
[Article in Chinese]

Abstract

Objective: To study of the quality standard about Jinshui Liujun decoction.

Methods: The chronic broncitis model of rat was induced by injecting LPS into rat's trachea. Then, the number of WBC, SV, PS were detected.

Results: Both Jinshui Liujun decoction and hesperidin can improve the content of PS and reduce the number of WBC. There were statistical difference between the therapeutic groups and the model group, and the changes of bronchi between the therapeutic group were similar. But the SV of hesperidin group was bigger than Jinshui Liujun decoction group, and the PS of hesperidin group was less than Jinshui Liujun decoction group.

Conclusion: It was feasible that the content of hesperidin in Jinshui Liujun decoction was as primary quality control index.

Publication types

  • English Abstract

MeSH terms

  • Angelica sinensis / chemistry
  • Animals
  • Bronchitis, Chronic* / drug therapy
  • Bronchitis, Chronic* / pathology
  • Citrus / chemistry
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / pharmacology*
  • Expectorants / pharmacology
  • Hesperidin / pharmacology*
  • Male
  • Phytotherapy
  • Pinellia / chemistry
  • Plants, Medicinal / chemistry*
  • Quality Control
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Drugs, Chinese Herbal
  • Expectorants
  • Hesperidin