Abstract
The effects of peptide derivatives as agonists or antagonists of formylpeptide receptors are described, taking into account the related cellular responses by neutrophils. These effects are related to the structure of peptide derivatives, some of which are potent anti HIV-1 agents. Finally, formylpeptide receptor models are depicted.
MeSH terms
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Amino Acid Sequence
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Animals
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Anti-HIV Agents / chemistry
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Anti-HIV Agents / pharmacology
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Humans
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Neutrophils / drug effects*
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Peptides / chemistry
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Peptides / pharmacology*
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Receptors, Formyl Peptide
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Receptors, Immunologic / agonists*
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Receptors, Immunologic / antagonists & inhibitors*
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Receptors, Immunologic / chemistry
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Receptors, Immunologic / metabolism
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Receptors, Peptide / agonists*
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Receptors, Peptide / antagonists & inhibitors*
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Receptors, Peptide / chemistry
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Receptors, Peptide / metabolism
Substances
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Anti-HIV Agents
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Peptides
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Receptors, Formyl Peptide
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Receptors, Immunologic
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Receptors, Peptide