Abstract
The traditional Chinese medicine Shundao Granules po markedly inhibited the formation of gastric ulcers induced by indomethacin, restraint and pyloric ligatin in rats. A decreased volume of gastric juice collected from pyloric ligated stomaches and a reduced level of gastric acid have been observed. The results showed that Shundao Granules had markedly analgesic action and significantly enhanced intestinal movement in mice, increased propulsive rate of small ingestion in mice.
MeSH terms
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Analgesics / pharmacology
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Animals
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Anti-Ulcer Agents / pharmacology*
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Anti-Ulcer Agents / therapeutic use
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Constipation / drug therapy
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Drugs, Chinese Herbal / pharmacology*
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Drugs, Chinese Herbal / therapeutic use
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Female
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Gastric Acid / metabolism
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Gastrointestinal Motility / drug effects*
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Guinea Pigs
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Indomethacin
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Male
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Mice
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Rats
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Rats, Sprague-Dawley
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Stomach Ulcer / chemically induced
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Stomach Ulcer / drug therapy*
Substances
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Analgesics
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Anti-Ulcer Agents
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Drugs, Chinese Herbal
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Indomethacin