Sesquiterpene lactones in a hairy root culture of Cichorium intybus

Z Naturforsch C J Biosci. 2002 Nov-Dec;57(11-12):994-7. doi: 10.1515/znc-2002-11-1207.

Abstract

A transformed root culture of Cichorium intybus L. (Asteraceae) was found to produce sesquiterpene lactones of guaiane and germacrane type. Lactucopicrin, 8-desoxylactucin and three sesquiterpene lactone glycosides: crepidiaside B, sonchuside A and ixerisoside D were isolated from the roots. The yield of 8-desoxylactucin reached 0.03 g l(-1) at the early stationary phase of the culture.

MeSH terms

  • Biomass
  • Cells, Cultured
  • Cichorium intybus / chemistry*
  • Cichorium intybus / growth & development
  • Lactones / chemistry
  • Lactones / isolation & purification
  • Models, Molecular
  • Molecular Structure
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Leaves / microbiology
  • Plant Roots / chemistry*
  • Plant Roots / growth & development
  • Sesquiterpenes / chemistry*
  • Sesquiterpenes / isolation & purification

Substances

  • Lactones
  • Plant Extracts
  • Sesquiterpenes