Abstract
A transformed root culture of Cichorium intybus L. (Asteraceae) was found to produce sesquiterpene lactones of guaiane and germacrane type. Lactucopicrin, 8-desoxylactucin and three sesquiterpene lactone glycosides: crepidiaside B, sonchuside A and ixerisoside D were isolated from the roots. The yield of 8-desoxylactucin reached 0.03 g l(-1) at the early stationary phase of the culture.
MeSH terms
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Biomass
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Cells, Cultured
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Cichorium intybus / chemistry*
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Cichorium intybus / growth & development
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Lactones / chemistry
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Lactones / isolation & purification
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Models, Molecular
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Molecular Structure
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification
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Plant Leaves / microbiology
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Plant Roots / chemistry*
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Plant Roots / growth & development
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Sesquiterpenes / chemistry*
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Sesquiterpenes / isolation & purification
Substances
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Lactones
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Plant Extracts
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Sesquiterpenes