Self-assembled oligonucleotide-polyester dendrimers

Chem Commun (Camb). 2002 Dec 21:(24):2954-5. doi: 10.1039/b209029e.

Abstract

A new approach to the controlled synthesis of multicomponent dendrimers is presented, in which three oligonucleotide-dendron conjugates were synthesized using solid phase techniques and hybridized to create a second generation polyester dendrimer with DNA as a core and bearing two types of peripheral functional groups.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Chromatography, High Pressure Liquid
  • DNA / chemical synthesis
  • DNA / chemistry
  • Nanotechnology
  • Oligonucleotides / chemical synthesis*
  • Oligonucleotides / chemistry
  • Polyesters / chemical synthesis*
  • Polyesters / chemistry
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Substances

  • Oligonucleotides
  • Polyesters
  • DNA