To explore the incidence and significance of myocardial bridge in the patients undertaken coronary angiography, 861 patients were retrospectively analyzed. Fourteen myocardial bridges was detected and the prevalence rate was 1.6%. All myocardial bridges were in left anterior descending branches and among which 1 with Grade I stenosis, 4 with Grade II stenosis and 9 with Grade III stenosis. All cases had clinical symptoms and electrocardiographic changes in myocardial ischemia. Eight cases were performed test of exercise and 7 were positive and 1 was suspected positive. Three patients examined nuclide myocardial perfusion showed anterior wall myocardial ischemia of left ventricle. After having been treated by beta-blocking agents, symotoms of angina pectoris were relieved obviously and after 0.5-6 year's follow-up, no acute myocardial infarction, sudden death, and acute heart failure occured in patients with myocardial bridge. The prognosis in patients with myocardial bridge was better than those with coronary heart diseases with stable stenosis. Myocardial bridge in coronary arteries may cause myocardial ischemia and angina, and therapy of beta-blocking agents is an effective treatment.