Papillary pneumocytoma of the lung simulating a pleomorphic adenoma

In Vivo. 2002 Sep-Oct;16(5):387-90.

Abstract

A rare case of papillary pneumocytoma of the lung is reported. The immunohistochemical positivities for EMA, cytokeratin and TTF-l strongly support the hypothesis that the neoplastic cells are originated from type 2 pneumocytes. The tumour also presented areas displaying stroma of non-specific mixoid appearance, simulating a benign tumour of the salivary gland type. We propose that these mixoid areas constitute structures of metaplastic origin.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / chemistry
  • Adenoma / pathology*
  • Adenoma / surgery
  • Adenoma, Pleomorphic / pathology*
  • Aged
  • Biomarkers, Tumor / analysis
  • Bronchial Neoplasms / chemistry
  • Bronchial Neoplasms / pathology*
  • Bronchial Neoplasms / surgery
  • Diagnosis, Differential
  • Humans
  • Keratins / analysis
  • Male
  • Mucin-1 / analysis
  • Nuclear Proteins / analysis
  • Radiography, Thoracic
  • Thyroid Nuclear Factor 1
  • Transcription Factors / analysis
  • Treatment Outcome

Substances

  • Biomarkers, Tumor
  • Mucin-1
  • Nuclear Proteins
  • Thyroid Nuclear Factor 1
  • Transcription Factors
  • Keratins