Beta-blocker-induced psoriasis: a rare side effect--a case report

Angiology. 2002 Nov-Dec;53(6):737-9. doi: 10.1177/000331970205300617.

Abstract

Beta blockers are one of the oral agents shown to decrease cardiovascular morbidity and mortality rates in randomized, controlled trials, and hence, they are widely used for the management of many cardiovascular situations. In terms of side effects there are 3 major modes of action: (1) contraction of smooth muscles, particularly of bronchi with nonselective agents; (2) exaggerated cardiac effects; and (3) central nervous system effects. There are also some rare side effects of beta blockers, some of which are unpredictable, but the others are related to mode of action at the cellular level. Beta-blocking agents may cause psoriaform eruptions and worsen existing psoriasis. Psoriasis may be an inconvenient side effect of beta blockade. Herein, we report a case of beta-blocker-induced psoriasis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adrenergic beta-Antagonists / adverse effects*
  • Adrenergic beta-Antagonists / therapeutic use
  • Aged
  • Atenolol / adverse effects
  • Atenolol / therapeutic use
  • Humans
  • Male
  • Metoprolol / adverse effects*
  • Metoprolol / therapeutic use
  • Psoriasis / chemically induced*

Substances

  • Adrenergic beta-Antagonists
  • Atenolol
  • Metoprolol