Discovery of one's human immunodeficiency virus (HIV) infection, or receiving a diagnosis of acquired immune deficiency syndrome (AIDS), sets in motion a variety of transitions for individuals. Transitions may be characterized by changes in identity or role, changes in physical capacity and functioning, changes in outlook, changes in relationships, changes in routine, etc. Workplaces also face transitions to deal with increasing numbers of workers who are infected with HIV. A model for vocational rehabilitation counselors to assist individuals living with HIV infection in adjusting to their transitions is presented, and resources for providing informational support of individuals and organizations are described.