Abstract
Genetic studies of embryo, ovule and flower development in Arabidopsis thaliana have led to the independent isolation of different mutant alleles of a single gene (SIN1/SUS1/CAF, now renamed DCL1) that encodes a complex RNA-processing enzyme. DCL1 shows similarity to the Dicer group of genes, which are required for RNA silencing in Drosophila and Caenorhabditis. These recent findings identify a novel but conserved mechanism of post-transcriptional gene regulation that is important for development in eukaryotes.
Publication types
-
Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
-
Alleles
-
Arabidopsis / genetics*
-
Arabidopsis / growth & development
-
Arabidopsis Proteins / genetics*
-
Arabidopsis Proteins / metabolism
-
Cell Cycle Proteins / genetics*
-
Cell Cycle Proteins / metabolism
-
Endoribonucleases / genetics*
-
Endoribonucleases / metabolism
-
Flowers / genetics
-
Flowers / growth & development
-
Genes, Plant / genetics
-
Mutation
-
RNA Interference
-
RNA, Plant / genetics
-
RNA, Plant / metabolism
-
Ribonuclease III
-
Seeds / genetics
-
Seeds / growth & development
Substances
-
Arabidopsis Proteins
-
Cell Cycle Proteins
-
RNA, Plant
-
Endoribonucleases
-
DCL1 protein, Arabidopsis
-
Ribonuclease III