Conduct problems, gender and adult psychiatric outcome of children with attention-deficit hyperactivity disorder

Br J Psychiatry. 2002 Nov:181:416-21. doi: 10.1192/bjp.181.5.416.

Abstract

Background: Attention-deficit hyperactivity disorder (ADHD) is a common childhood condition, and is more prevalent in boys. The adult outcome of girls with ADHD has never been studied.

Aims: To identify predictors for adult psychiatric outcome of children with ADHD, including gender and comorbidity.

Method: Children aged 4-15 years, referred for hyperactivity/inattention and treated with stimulants were included (n=208). The Psychiatric Case Register provided follow-up data on psychiatric admissions in adulthood until a mean age of 31 years.

Results: A total of 47 cases (22.6%) had a psychiatric admission in adulthood. Conduct problems in childhood were predictive (hazard ratio HR=2.3; 95% CI 1.22-4.33). Girls had a higher risk compared with boys (HR=2.4; 95% CI 1.1-5.6).

Conclusions: Girls with ADHD had a higher risk of adult psychiatric admission than boys. Conduct problems were also associated with a higher risk. Girls with ADHD with conduct problems had a very high risk of a psychiatric admission in adulthood.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Attention Deficit Disorder with Hyperactivity / psychology*
  • Child
  • Child, Preschool
  • Conduct Disorder / psychology
  • Female
  • Follow-Up Studies
  • Hospitalization / statistics & numerical data
  • Humans
  • Male
  • Mental Disorders / etiology
  • Prognosis
  • Proportional Hazards Models
  • Sex Factors