Consequences of EHEC colonisation in humans and cattle

Int J Med Microbiol. 2002 Sep;292(3-4):169-83. doi: 10.1078/1438-4221-00202.

Abstract

While many factors have been associated with human EHEC infection, the full role these play in both human and ruminant hosts are not yet clear despite much investigation. It is hoped that the continued intense international research effort into EHEC will provide further insights into the commensal versus pathogenic lifestyles of E. coli and lead to approaches to reduce EHEC carriage in ruminants as well as prevent or treat human disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adhesins, Bacterial / metabolism
  • Adhesins, Escherichia coli / metabolism
  • Animals
  • Bacterial Proteins / metabolism
  • Carrier Proteins / metabolism
  • Cattle
  • Cattle Diseases / microbiology*
  • Disease Reservoirs / veterinary
  • Escherichia coli Infections / metabolism
  • Escherichia coli Infections / veterinary*
  • Escherichia coli O157 / growth & development*
  • Escherichia coli O157 / metabolism
  • Escherichia coli O157 / pathogenicity
  • Escherichia coli Proteins*
  • Fimbriae, Bacterial / metabolism
  • Gastrointestinal Diseases / microbiology
  • Gastrointestinal Diseases / veterinary*
  • Humans
  • Shiga Toxins / biosynthesis
  • Shiga Toxins / metabolism

Substances

  • Adhesins, Bacterial
  • Adhesins, Escherichia coli
  • Bacterial Proteins
  • Carrier Proteins
  • Escherichia coli Proteins
  • Shiga Toxins
  • eaeA protein, E coli