Abstract
The I allele of the angiotensin I-converting enzyme (ACE) gene is associated with lower ACE activity and endurance performance; an excess occurs in elite distance runners, rowers, and mountaineers, perhaps secondary to enhanced muscle efficiency. Conversely, the D allele is associated with training-related strength gain and elite power-oriented performance secondary to increased ACE and angiotensin II, a growth factor.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Alleles
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Bradykinin / genetics
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Bradykinin / metabolism
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Genetic Markers
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Genetics, Population
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Genotype
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Humans
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Peptidyl-Dipeptidase A / genetics*
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Peptidyl-Dipeptidase A / metabolism
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Physical Endurance / genetics*
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Physical Endurance / physiology
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Polymorphism, Genetic*
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Task Performance and Analysis*
Substances
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Genetic Markers
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Peptidyl-Dipeptidase A
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Bradykinin