Previous event-related potential (ERP) studies of eye movements were restricted to saccades, the rapid conjugate movements used to change direction of fixation. Our study explored ERP activity for vergence eye movements used for the adjustment of the angle of the visual axes to the distance of the object. These movements are essential when exploring the natural 3D world. Subjects made the following visually guided movements to LED targets: pure convergence or divergence along the median plane, pure lateral saccades within the same distance, and combined movements (lateral and divergent or convergent). ERPs were recorded from 14 surface electrodes and were analyzed for 200 ms prior to the onset of the eye movement. The highest activation was observed prior to vergence. Activation was diffused and peaked at 50 ms prior to the onset of vergence. Combined vergence and sacccadic movements revealed a composite pattern of ERP activity from both saccades and pure vergence. These findings suggest a cortical substrate for vergence eye movements in humans that is engaged in the natural exploration of visual space.