[Familial idiopathic hypertrophic osteoarthropathy and atopic dermatitis (Currarino's disease)]

Arch Pediatr. 2002 Sep;9(9):921-4. doi: 10.1016/s0929-693x(02)00024-6.
[Article in French]

Abstract

Case report: Two brothers with a Currarino's disease are reported. Patients characteristics included a dysmorphic syndrome, cranial suture defects, hypertrophic osteoarthropathy and severe chronic eczema.

Comments: Consanguinity of parents suggests an autosomal recessive inheritance.

Conclusion: Currarino's disease is a rare unknown constitutional syndrome. The age of beginning of the disease, the cranial suture defects and the chronic eczema allow to distinguish it from the others primary hypertrophic osteoarthropathies.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Abnormalities, Multiple / diagnosis
  • Abnormalities, Multiple / genetics*
  • Age of Onset
  • Consanguinity
  • Cranial Sutures / abnormalities*
  • Dermatitis, Atopic / diagnosis
  • Dermatitis, Atopic / genetics*
  • Diagnosis, Differential
  • Genes, Recessive / genetics
  • Humans
  • Infant
  • Male
  • Osteoarthropathy, Primary Hypertrophic / diagnosis
  • Osteoarthropathy, Primary Hypertrophic / genetics*
  • Syndrome