Using bioinformatics to identify kidney genes

Nephrol Dial Transplant. 2002:17 Suppl 9:62-4. doi: 10.1093/ndt/17.suppl_9.62.

Abstract

Online knowledge of genes involved in mouse kidney development is available from the literature (PubMed) and text-based (Kidney Development and Mouse Gene Expression-GXD) databases. Further information is in gene databases of other organisms having tissues homologous to the metanephros (e.g. Drosophila Malpighian tubules; tools are available for identifying mouse homologues of non-mouse genes) and from tissues homologous to those in the developing kidney (e.g. mesothelium that, like nephrons, arises from a mesenchyme to epithelial transition). Future databases will also include graphical data, and this knowledge will provide a further level of insight. These databases and tools are discussed here.

MeSH terms

  • Animals
  • Computational Biology*
  • Databases as Topic
  • Gene Expression
  • Genes*
  • Growth
  • Internet
  • Kidney / physiology*
  • Mice