The prevention of the occupational skin disease is essential to avoid some clinical complications and to preserve job. The suppression of the responsible factor is rarely possible at work, but when it is possible, it is efficient. The practice of real orders of prevention is the best way to proceed, writing individual and collective prevention prescriptions, which have to be very precise and adapted to every case during one sufficient time to get a good adherence of the patients. The implementation of the prevention consists of a set of advices on the prevention measures carrying on the environment, the processes or the work tools, the bad habits, and advices about the professional gestures to avoid and about the convenient information on the manner to use the means of individual prevention (gloves, protective creams and moisturizers) recommended and adapted to each work sequence.