Mimicking gangliosides by design: mimics of GM1 headgroup

Neurochem Res. 2002 Aug;27(7-8):539-45. doi: 10.1023/a:1020251428217.

Abstract

Detailed knowledge of the three-dimensional structure of ganglioside headgroups has allowed the successful design of structural and functional mimics of ganglioside GMI oligosaccharide. Our recent work in this area is reviewed in this paper.

Publication types

  • Review

MeSH terms

  • Carbohydrate Conformation
  • Carbohydrate Sequence
  • G(M1) Ganglioside / chemistry*
  • Molecular Mimicry*
  • Molecular Sequence Data

Substances

  • G(M1) Ganglioside