The use of a sutureless anastomotic device recently has been reported for the construction of the proximal anastomoses during aortocoronary bypass surgery. In this report, we describe the first reported application of this device for the sutureless aortic anastomosis of an aortosuperior mesenteric artery saphenous vein graft. Sutureless anastomoses reduce the need for extensive dissection of the inflow vessel and may be performed rapidly and without blood loss.