Foot-and-mouth disease virus: biology and prospects for disease control

Microbes Infect. 2002 Sep;4(11):1183-92. doi: 10.1016/s1286-4579(02)01644-1.

Abstract

Foot-and-mouth disease virus (FMDV) is the causative agent of a disease that constitutes one of the main animal health concerns, as evidenced by the devastating outbreaks that occurred in different areas of the world over the last few years. In this review, we summarise important features of FMDV, aspects of its interactions with cells and hosts as well as current and new strategies for FMD control by vaccination.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases / epidemiology
  • Cattle Diseases / prevention & control
  • Foot-and-Mouth Disease / epidemiology
  • Foot-and-Mouth Disease / immunology
  • Foot-and-Mouth Disease / prevention & control*
  • Foot-and-Mouth Disease Virus / genetics
  • Foot-and-Mouth Disease Virus / growth & development
  • Foot-and-Mouth Disease Virus / pathogenicity*
  • Gene Expression
  • Host-Parasite Interactions
  • Infection Control / trends
  • Models, Genetic
  • Models, Structural
  • RNA, Viral / genetics
  • RNA, Viral / metabolism
  • Sheep
  • Sheep Diseases / epidemiology
  • Sheep Diseases / prevention & control
  • Viral Vaccines / classification
  • Viral Vaccines / genetics

Substances

  • RNA, Viral
  • Viral Vaccines