Complete cDNA sequences of the HLA-DRB1*0402 and DRB1*11041 alleles

Eur J Immunogenet. 2002 Oct;29(5):453-5. doi: 10.1046/j.1365-2370.2002.00354.x.

Abstract

Since the development of the polymerase chain reaction, most HLA class II allele sequencing has been exclusively focused on the highly polymorphic exon 2. We present here the full cDNA sequences of two HLA-DRB1 alleles, DRB1*0402 and DRB1*11041, both of which were previously only available as partial sequences. HLA-DRB1*11041 was found to be completely homologous to DRB1*11011 in exons 1, 3, 4, 5 and 6 and HLA-DRB1*0402 was found to be identical to DRB1*04011 in exons 1, 3, 4, 5 and 6.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Base Sequence
  • DNA, Complementary / genetics
  • Exons
  • HLA-DR Antigens / genetics*
  • HLA-DRB1 Chains
  • Humans
  • Molecular Sequence Data

Substances

  • DNA, Complementary
  • HLA-DR Antigens
  • HLA-DRB1 Chains
  • HLA-DRB1*04:02 antigen
  • HLA-DRB1*11:01:01 antigen

Associated data

  • GENBANK/AJ297586
  • GENBANK/AJ297587