Four new sesquiterpenoid derivatives from the heartwood of Mansonia gagei

J Nat Prod. 2002 Sep;65(9):1332-5. doi: 10.1021/np020024e.

Abstract

Four new sesquiterpenoid derivatives named mansonones N (1), O (2), P (3), and Q (4) were isolated from a dichloromethane extract of the heartwood of Mansonia gagei, a plant used in folk medicine in Thailand. Their structures were resolved on the basis of spectrometric data interpretation and the single-crystal X-ray analysis of 1 and 2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromatography, Liquid
  • DNA-Binding Proteins
  • Malvaceae / chemistry*
  • Medicine, Traditional*
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Sesquiterpenes / chemistry*
  • Sesquiterpenes / isolation & purification*
  • Stereoisomerism
  • Thailand

Substances

  • DNA-Binding Proteins
  • Sesquiterpenes
  • XRCC8 protein, human