Abstract
Ion channels selective for potassium or chloride ions are present in inner mitochondrial membranes. They are probably important in cellular events such as regulation of organelle volume changes. Additionally, mitochondrial potassium channels are targets for potassium channel openers and antidiabetic sulfonylureas. This review describes properties, and current hypotheses concerning the functional role of mitochondrial ion channels.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adenosine Triphosphate / metabolism
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Chloride Channels / metabolism
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Ion Channels / drug effects
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Ion Channels / metabolism*
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Mitochondria / drug effects
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Mitochondria / metabolism*
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Potassium Channels / metabolism
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Sulfonylurea Compounds / pharmacology
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Synaptic Vesicles / metabolism
Substances
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Chloride Channels
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Ion Channels
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Potassium Channels
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Sulfonylurea Compounds
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Adenosine Triphosphate