Four new compounds from the seeds of Cassia fistula

J Nat Prod. 2002 Aug;65(8):1165-7. doi: 10.1021/np020003k.

Abstract

Four new compounds, 5-(2-hydroxyphenoxymethyl)furfural (1), (2'S)-7-hydroxy-5- hydroxymethyl-2-(2'-hydroxypropyl)chromone (2), benzyl 2-hydroxy-3,6-dimethoxybenzoate (3), and benzyl 2beta-O-D-glucopyranosyl-3,6-dimethoxybenzoate (4), together with four known compounds, 5-hydroxymethylfurfural, (2'S)-7-hydroxy-2-(2'-hydroxypropyl)-5-methylchromone, and two oxyanthraquinones, chrysophanol and chrysophanein, were isolated and identified from the seeds of Cassia fistula. The structures of 1-4 were determined on the basis of spectral data explanation, and the synthesis of compound 1 was carried out.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromones / chemistry
  • Chromones / isolation & purification*
  • Fabaceae / chemistry*
  • Furaldehyde / analogs & derivatives
  • Furaldehyde / chemistry
  • Furaldehyde / isolation & purification*
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Hydroxybenzoate Ethers
  • Hydroxybenzoates / chemistry
  • Hydroxybenzoates / isolation & purification*
  • Infrared Rays
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plants, Medicinal / chemistry*
  • Seeds / chemistry
  • Stereoisomerism
  • Taiwan

Substances

  • 5-(2-hydroxyphenoxymethyl)furfural
  • 7-hydroxy-5- hydroxymethyl-2-(2'-hydroxypropyl)chromone
  • Chromones
  • Glucosides
  • Hydroxybenzoate Ethers
  • Hydroxybenzoates
  • benzyl 2-O-glucopyranosyl-3,6-dimethoxybenzoate
  • benzyl 2-hydroxy-3,6-dimethoxybenzoate
  • Furaldehyde