Incidence and short-term outcome of cerebral infarction in young adults in western Norway

Stroke. 2002 Aug;33(8):2105-8. doi: 10.1161/01.str.0000023888.43488.10.

Abstract

Background and purpose: We sought to determine the incidence and short-term outcome of people aged 15 to 49 years with first-ever cerebral infarction in 1988-1997 in Hordaland County, Norway.

Methods: Cases were found from computer search of hospital registries and detailed review of patient records. Stroke subtype was classified according to the major intracranial artery affected. Short-term outcome was evaluated by the modified Rankin Scale (mRS).

Results: A total of 96 women and 136 men met the inclusion criteria. The average annual incidence was 11.4/100 000. Women outnumbered men among those aged <30 years (P=0.059); men predominated among those aged > or =30 years (P=0.004). A total of 148 patients had anterior circulation infarction (64%), and 84 had posterior circulation infarction (36%) (P<0.001). Patients with posterior circulation infarction had better mRS score at discharge (P=0.005). Eighty percent had favorable outcome (mRS score < or =2). The 30-day case fatality rate was 3.4%. The recurrence rate in hospital was 2.2%.

Conclusions: The incidence was in the lower range compared with other reports from western Europe. Although men predominated, there was a strong trend toward more women among patients aged <30 years. Short-term outcome was generally good. Patients with posterior circulation infarction had significantly better short-term outcome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Cerebral Infarction / classification
  • Cerebral Infarction / complications
  • Cerebral Infarction / diagnosis
  • Cerebral Infarction / epidemiology*
  • Cerebral Infarction / therapy
  • Female
  • Hospital Mortality
  • Humans
  • Incidence
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Nervous System Diseases / diagnosis
  • Nervous System Diseases / etiology
  • Norway / epidemiology
  • Observer Variation
  • Poisson Distribution
  • Recurrence
  • Registries
  • Sex Distribution
  • Statistics, Nonparametric
  • Survival Rate
  • Survivors
  • Tomography, X-Ray Computed
  • Treatment Outcome