Enantioselective formation of (R)-9-HPODE and (R)-9-HPOTrE in marine green alga Ulva conglobata

Bioorg Med Chem. 2002 Oct;10(10):3171-3. doi: 10.1016/s0968-0896(02)00212-2.

Abstract

When linoleic and linolenic acid were incubated with a crude enzyme of marine green alga Ulva conglobata, the corresponding (R)-9-hydroperoxy-(10E, 12Z)-10, 12-octadecadienoic acid [(R)-9-HPODE] and (R)-9-hydroperoxy-(10E, 12Z, 15Z)-10, 12, 15-octadecatrienoic acid [(R)-9-HPOTrE] were formed with a high enantiomeric excess (>99%), respectively.

MeSH terms

  • Chlorophyta / enzymology
  • Chlorophyta / metabolism*
  • Chromatography, High Pressure Liquid
  • Linoleic Acid / metabolism
  • Linoleic Acids / biosynthesis*
  • Linoleic Acids / chemistry
  • Lipid Peroxides / biosynthesis*
  • Lipid Peroxides / chemistry
  • Stereoisomerism
  • alpha-Linolenic Acid / metabolism

Substances

  • Linoleic Acids
  • Lipid Peroxides
  • alpha-Linolenic Acid
  • 9-hydroperoxy-10,12,15-octadecatrienoic acid
  • 9-hydroperoxy-11,12-octadecadienoic acid
  • Linoleic Acid