Coumarins from the heartwoods of Mansonia gagei Drumm

Pattara Tiew; Apiruk Puntumchai; Udom Kokpol; Warinthorn Chavasiri

doi:10.1016/s0031-9422(02)00194-2

Coumarins from the heartwoods of Mansonia gagei Drumm

Phytochemistry. 2002 Aug;60(8):773-6. doi: 10.1016/s0031-9422(02)00194-2.

Authors

Pattara Tiew¹, Apiruk Puntumchai, Udom Kokpol, Warinthorn Chavasiri

Affiliation

¹ Natural Products Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.

PMID: 12150797
DOI: 10.1016/s0031-9422(02)00194-2

Abstract

Three coumarins and three known mansonones were isolated from the heartwood of Mansonia gagei Drumm. The structures of the three coumarins were elucidated as 3,8-dimethyl-5-isopropyl-6-methoxycoumarin (mansonrin A) 3,8-dimethyl-5-isopropyl-6-hydroxycoumarin (mansorin B) and 2,3-dihydro-3,6,9-trimethyl naphtho[1,8-bc]pyran-7-oxa-8-one (mansorin C) by analyses of physical properties and spectroscopic data. The cytotoxicity of the isolated compounds against brine shrimp Artemia salina Linn. was also evaluated.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Coumarins / chemistry
Coumarins / isolation & purification*
Malvaceae / chemistry*
Molecular Structure
Spectrum Analysis

Substances

3,8-dimethyl-5-isopropyl-6-methoxycoumarin
Coumarins