Cross-infection due to imipenem-resistant Bacteroides fragilis associated with a totally implantable venous port

J Clin Microbiol. 2002 Aug;40(8):3032-4. doi: 10.1128/JCM.40.8.3032-3034.2002.

Abstract

Four patients in an oncology ward developed Bacteroides fragilis bacteremia over a 12-day period. Cross-infection between two of them, due to an imipenem-resistant strain, was demonstrated by epidemiological investigation and genotypic typing methods (arbitrarily primed PCR fingerprinting and nucleotide sequencing of the cfiA genes and upstream IS1186/IS1168 elements).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bacteremia / epidemiology
  • Bacteremia / microbiology
  • Bacterial Proteins*
  • Bacterial Typing Techniques
  • Bacteroides Infections / epidemiology
  • Bacteroides Infections / microbiology
  • Bacteroides fragilis / classification*
  • Bacteroides fragilis / drug effects*
  • Bacteroides fragilis / genetics
  • Catheterization, Central Venous / adverse effects*
  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • DNA, Bacterial / analysis
  • Drug Resistance, Bacterial
  • Female
  • Genotype
  • Humans
  • Imipenem / pharmacology*
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Neoplasms / complications
  • Sequence Analysis, DNA
  • Thienamycins / pharmacology*
  • beta-Lactamases / genetics

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • Thienamycins
  • Imipenem
  • beta-Lactamases
  • carbapenemase

Associated data

  • GENBANK/AF429432