Chromosome Organization: Reaching out to Embrace New Models

Curr Biol. 2002 Jul 9;12(13):R446-8. doi: 10.1016/s0960-9822(02)00941-7.

Abstract

New information on the architecture of protein complexes involved in the dynamic organization of chromosomes challenges existing models of their structures and provides fresh insight into their mechanisms of action.

Publication types

  • Review

MeSH terms

  • Acid Anhydride Hydrolases
  • Adenosine Triphosphatases / metabolism
  • Cell Cycle Proteins / metabolism
  • Chondroitin Sulfate Proteoglycans*
  • Chromosomal Proteins, Non-Histone / metabolism
  • Chromosomes, Fungal / chemistry*
  • Chromosomes, Fungal / metabolism
  • Cohesins
  • DNA Repair Enzymes*
  • DNA Replication
  • DNA, Fungal / chemistry
  • DNA-Binding Proteins / chemistry*
  • DNA-Binding Proteins / metabolism
  • Dimerization
  • Fungal Proteins
  • Humans
  • MRE11 Homologue Protein
  • Models, Molecular
  • Multiprotein Complexes
  • Nuclear Proteins / chemistry*
  • Nuclear Proteins / metabolism
  • Nucleic Acid Conformation*
  • Protein Conformation

Substances

  • Cell Cycle Proteins
  • Chondroitin Sulfate Proteoglycans
  • Chromosomal Proteins, Non-Histone
  • DNA, Fungal
  • DNA-Binding Proteins
  • Fungal Proteins
  • MRE11 protein, human
  • Multiprotein Complexes
  • Nuclear Proteins
  • SMC3 protein, human
  • condensin complexes
  • structural maintenance of chromosome protein 1
  • MRE11 Homologue Protein
  • Acid Anhydride Hydrolases
  • RAD50 protein, human
  • Adenosine Triphosphatases
  • DNA Repair Enzymes