Paradoxical response to apomorphine in a case of atypical parkinsonism

Mov Disord. 2002 May;17(3):604-6. doi: 10.1002/mds.10113.

Abstract

We describe a patient with clinical signs of parkinsonism showing a paradoxical response to apomorphine injection. We discuss possible pathogenetic mechanisms with regard to the literature and suggest the diagnosis of a striatonigral degeneration at an early stage.

Publication types

  • Case Reports

MeSH terms

  • Antiparkinson Agents*
  • Apomorphine*
  • Dopamine Agonists / therapeutic use*
  • Humans
  • Levodopa / therapeutic use
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Parkinsonian Disorders / diagnosis*
  • Parkinsonian Disorders / drug therapy
  • Tomography, Emission-Computed, Single-Photon
  • Treatment Failure

Substances

  • Antiparkinson Agents
  • Dopamine Agonists
  • Levodopa
  • Apomorphine