[Pseudomonas aeruginosa corneal abscess refractory to fluoroquinolones]

Arch Soc Esp Oftalmol. 2002 Jul;77(7):397-9.
[Article in Spanish]

Abstract

Purpose/method: To report a clinical case of a 21-year old male with a severe corneal abscess due to Pseudomonas aeruginosa refractory to intensive treatment with topical Ciprofloxacin.

Results/conclusions: A corneal scrapping performed after a wash-out period showed Pseudomonas aeruginosa specimens, which were not sensitive to any of the fluoroquinolones tested. A fortified topical treatment with Ceftazidime healed the corneal abscess. Nowadays, the possibility of resistance to fluoroquinolones should be kept in mind, and we recommend treatment guided by the results of a microbiological study in severe and sight-threatening cases.

Publication types

  • Case Reports

MeSH terms

  • Abscess / drug therapy
  • Abscess / microbiology*
  • Adult
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use*
  • Anti-Infective Agents / pharmacology*
  • Anti-Infective Agents / therapeutic use
  • Ceftazidime / pharmacology
  • Ceftazidime / therapeutic use*
  • Ciprofloxacin / pharmacology*
  • Ciprofloxacin / therapeutic use
  • Contact Lenses, Hydrophilic
  • Corneal Ulcer / drug therapy
  • Corneal Ulcer / microbiology*
  • Drug Resistance, Microbial
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / microbiology*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Pseudomonas Infections / drug therapy
  • Pseudomonas Infections / microbiology*
  • Pseudomonas aeruginosa / drug effects*

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Ciprofloxacin
  • Ceftazidime