Abstract
Purpose/method:
To report a clinical case of a 21-year old male with a severe corneal abscess due to Pseudomonas aeruginosa refractory to intensive treatment with topical Ciprofloxacin.
Results/conclusions:
A corneal scrapping performed after a wash-out period showed Pseudomonas aeruginosa specimens, which were not sensitive to any of the fluoroquinolones tested. A fortified topical treatment with Ceftazidime healed the corneal abscess. Nowadays, the possibility of resistance to fluoroquinolones should be kept in mind, and we recommend treatment guided by the results of a microbiological study in severe and sight-threatening cases.
MeSH terms
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Abscess / drug therapy
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Abscess / microbiology*
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Adult
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use*
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Anti-Infective Agents / pharmacology*
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Anti-Infective Agents / therapeutic use
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Ceftazidime / pharmacology
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Ceftazidime / therapeutic use*
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Ciprofloxacin / pharmacology*
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Ciprofloxacin / therapeutic use
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Contact Lenses, Hydrophilic
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Corneal Ulcer / drug therapy
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Corneal Ulcer / microbiology*
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Drug Resistance, Microbial
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Eye Infections, Bacterial / drug therapy
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Eye Infections, Bacterial / microbiology*
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Humans
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Male
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Microbial Sensitivity Tests
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Pseudomonas Infections / drug therapy
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Pseudomonas Infections / microbiology*
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Pseudomonas aeruginosa / drug effects*
Substances
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Anti-Bacterial Agents
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Anti-Infective Agents
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Ciprofloxacin
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Ceftazidime