The accelerated clearance on repeated injection of pegylated liposomes in rats: laboratory and histopathological study

Cell Mol Biol Lett. 2002;7(2):286.

Authors

Tatsuhiro Ishida¹, Ryuhei Maeda, Masako Ichihara, Yasuko Mukai, Yoko Motoki, Yoshie Manabe, Kenji Irimura, Hiroshi Kiwada

Affiliation

¹ Department of Pharmacokinetics and Biopharmaceutics, The University of Tokushima, Tokushima 770-8505, Japan. ishida@ph.tokushima-u.ac.jp

PMID: 12097957

No abstract available

MeSH terms

Animals
Drug Carriers
Humans
Injections, Intravenous
Liposomes
Liver / metabolism
Metabolic Clearance Rate
Models, Animal
Polyethylene Glycols / pharmacokinetics*
Rats
Spleen / metabolism

Substances

Drug Carriers
Liposomes
Polyethylene Glycols