[Immunotropic properties of exoglycan obtained from the marine micro-organism Vibrio alginolyticus]

T P Smolina; R P Gorshkova; E L Nazarenko; L A Ivanushko; T S Zaporozhets; N N Besednova

[Immunotropic properties of exoglycan obtained from the marine micro-organism Vibrio alginolyticus]

Antibiot Khimioter. 2002;47(1):7-11.

[Article in Russian]

Authors

T P Smolina¹, R P Gorshkova, E L Nazarenko, L A Ivanushko, T S Zaporozhets, N N Besednova

Affiliation

¹ Research Institute of Epidemiology and Microbiology, Siberian Branch, Russian Academy of Medical Sciences, Vladivostok.

PMID: 12077940

Abstract

Immune system modulating activity of exoglycane isolated from culture media of Vibrio alginolyticus (strain 945-80) was investigated. The substance demonstrated stimulating activity on the humoral and cell immune system, potentiated phagocyte activity of macrophage and neutrophils, increased survival index of the animals infected by Gram-positive and Gram-negative bacteria.

Publication types

English Abstract

MeSH terms

Adjuvants, Immunologic / pharmacology*
Animals
Antibody Formation / drug effects
Bacterial Infections / immunology*
Bacterial Infections / mortality
Guinea Pigs
Hypersensitivity, Delayed / immunology
Immunity, Cellular / drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Phagocytosis / drug effects
Polysaccharides / isolation & purification*
Vibrio / chemistry*

Substances

Adjuvants, Immunologic
Polysaccharides