Abstract
There are surprising similarities between how animals and plants perceive pathogens. In animals, innate immunity is based on the recognition of pathogen-associated molecular patterns. This is mediated by the Toll-like receptor (TLR) family, which rapidly induce the innate immunity response, a first line of defence against infectious disease. Plants have highly sensitive perception systems for general elicitors and they respond to these stimuli with a defence response. One of these general elicitors is flagellin, the main component of the bacterial flagellum. Genetic analysis in Arabidopsis has shown that FLS2, which encodes a receptor-like kinase, is essential for flagellin perception. FLS2 shares homology with the TLR family, and TLR5 is responsible for flagellin perception in mammals.
MeSH terms
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Animals
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Arabidopsis Proteins*
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Bacteria / genetics
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Bacteria / growth & development
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Drosophila Proteins*
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Evolution, Molecular
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Flagellin / genetics
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Flagellin / immunology
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Flagellin / metabolism*
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Fungi / genetics
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Fungi / growth & development
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Immunity, Innate / immunology
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Membrane Glycoproteins / genetics
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Membrane Glycoproteins / physiology
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Models, Biological
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Plant Diseases / genetics
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Plant Diseases / microbiology
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Plants / genetics
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Plants / microbiology*
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Protein Kinases / genetics
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Protein Kinases / physiology
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Receptors, Cell Surface / genetics
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Receptors, Cell Surface / physiology
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Signal Transduction
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Toll-Like Receptor 5
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Toll-Like Receptors
Substances
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Arabidopsis Proteins
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Drosophila Proteins
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Membrane Glycoproteins
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Receptors, Cell Surface
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Toll-Like Receptor 5
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Toll-Like Receptors
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Flagellin
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Protein Kinases
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FLS2 protein, Arabidopsis