Mechanisms of immunity against rickettsiae. New perspectives and opportunities offered by unusual intracellular parasites

Gustavo Valbuena; Hui Min Feng; David H Walker

doi:10.1016/s1286-4579(02)01581-2

Mechanisms of immunity against rickettsiae. New perspectives and opportunities offered by unusual intracellular parasites

Microbes Infect. 2002 May;4(6):625-33. doi: 10.1016/s1286-4579(02)01581-2.

Authors

Gustavo Valbuena¹, Hui Min Feng, David H Walker

Affiliation

¹ Department of Pathology and WHO Collaborating Center for Tropical Diseases, University of Texas Medical Branch, 301 University Boulevard, Galveston 77555-0609, USA.

PMID: 12048032
DOI: 10.1016/s1286-4579(02)01581-2

Abstract

Investigation of the biology, pathology and immunology of rickettsial diseases offers new insights useful not only for the field of rickettsiology, but more importantly for the understanding of general principles of host-intracellular parasite relationships and, in particular, the immune interaction between endothelial cells and immune cells in the context of infection.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Animals
Antibody Formation
Endothelium / immunology
Humans
Immunity, Cellular
Mice
Rickettsia / immunology*
Rickettsia / metabolism
Rickettsia Infections / immunology*
Rickettsia Infections / pathology
Rickettsia Infections / prevention & control
Rickettsial Vaccines / immunology*

Substances

Rickettsial Vaccines

Grants and funding

AI 21242/AI/NIAID NIH HHS/United States