Efficacy of teicoplanin and imipenem on respiratory infections in high risk patients

G Piu; G Aresu; M Pautasso; G Garau; S Melis; S Ceccio; M Morini; A Palomba

Efficacy of teicoplanin and imipenem on respiratory infections in high risk patients

J Chemother. 1991 Jan:3 Suppl 1:222-3.

Authors

G Piu¹, G Aresu, M Pautasso, G Garau, S Melis, S Ceccio, M Morini, A Palomba

Affiliation

¹ Laboratorio Microbiologia e Virologia, Ospedale S Michele, Cagliari, Italy.

PMID: 12041770

Abstract

The efficacy of teicoplanin and imipenem was assayed on microorganisms, mainly hospital opportunistic organisms, resistant to common therapy, isolated from bronchoaspirates of high risk hospitalized patients. Imipenem has shown remarkable activity against all isolated microorganisms with sensitivities ranging from 91.93% against Acinetobacter calcoaceticus to 75.86% against Pseudomonas sp. Teicoplanin has shown excellent activity against Staphylococcus aureus (sensitivity 83.66%).

MeSH terms

Acinetobacter Infections / drug therapy*
Anti-Bacterial Agents / administration & dosage
Anti-Bacterial Agents / pharmacology*
Cross Infection / drug therapy
Drug Therapy, Combination
Humans
Imipenem / administration & dosage
Imipenem / pharmacology*
Microbial Sensitivity Tests
Pseudomonas Infections / drug therapy*
Risk Factors
Staphylococcal Infections / drug therapy*
Teicoplanin / administration & dosage
Teicoplanin / pharmacology*
Thienamycins / administration & dosage
Thienamycins / pharmacology*

Substances

Anti-Bacterial Agents
Thienamycins
Teicoplanin
Imipenem