Betahistine inhibits food intake in rats

Pol J Pharmacol. 2001 Nov-Dec;53(6):701-7.

Abstract

Betahistine, administered intraperitoneally, decreased, in a dose-dependent manner and in a statistically significant degree, total food intake in different experimental models in rats.

MeSH terms

  • Animals
  • Betahistine / pharmacology*
  • Dose-Response Relationship, Drug
  • Eating / drug effects*
  • Histamine Agonists / pharmacology*
  • Histamine Antagonists / pharmacology*
  • Infusions, Parenteral
  • Male
  • Rats
  • Rats, Wistar
  • Receptors, Histamine H1 / drug effects
  • Receptors, Histamine H3 / drug effects

Substances

  • Histamine Agonists
  • Histamine Antagonists
  • Receptors, Histamine H1
  • Receptors, Histamine H3
  • Betahistine