[Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin]

Naofumi Fukuda; Yoko Shimohakamada; Yoshitaka Nakamori; Takayuki Tominaga; Kenji Shinohara; Toru Takahashi; Eiichi Oeda; Yutaka Sato

[Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin]

Rinsho Ketsueki. 2002 Mar;43(3):199-203.

[Article in Japanese]

Authors

Naofumi Fukuda¹, Yoko Shimohakamada, Yoshitaka Nakamori, Takayuki Tominaga, Kenji Shinohara, Toru Takahashi, Eiichi Oeda, Yutaka Sato

Affiliation

¹ Division of Hematology, Department of Medicine, Yamaguchi Prefecture Central Hospital.

PMID: 11979753

Abstract

We describe a case of thoracic aortic aneurysm complicated by chronic disseminated intravascular coagulation (DIC). Initially the DIC was controlled successfully by administration of gabexate mesilate and dalteparin. However, because these drugs were given intravenously, the patient could not be discharged. Subsequently, the DIC was treated successfully by changing to orally administered camostat mesilate, warfarin and aspirin, which allowed the patient to leave hospital.

Publication types

Case Reports

MeSH terms

Administration, Oral
Aged
Anticoagulants / administration & dosage*
Aortic Aneurysm, Thoracic / complications
Aortic Aneurysm, Thoracic / drug therapy*
Aspirin / administration & dosage*
Chronic Disease
Disseminated Intravascular Coagulation / complications
Disseminated Intravascular Coagulation / drug therapy*
Drug Therapy, Combination
Esters
Gabexate* / analogs & derivatives*
Guanidines / administration & dosage*
Humans
Male
Warfarin / administration & dosage*

Substances

Anticoagulants
Esters
Guanidines
camostat
Gabexate
Warfarin
Aspirin