[Attachment and growth of cultured fibroblast cells on chitosan/PHEA-blended hydrogels]

Ai-Ping Zhu; Shi-Quan Wang; Da-Ming Cheng; Qiang Chen; Chong-Jiang Liu; Jian Shen; Si-Cong Lin

[Attachment and growth of cultured fibroblast cells on chitosan/PHEA-blended hydrogels]

Sheng Wu Gong Cheng Xue Bao. 2002 Jan;18(1):109-11.

[Article in Chinese]

Authors

Ai-Ping Zhu¹, Shi-Quan Wang, Da-Ming Cheng, Qiang Chen, Chong-Jiang Liu, Jian Shen, Si-Cong Lin

Affiliation

¹ Department of Polymer Science and Engineering, Nanjing University, Nanjing 210093, China.

PMID: 11977588

Abstract

The chitosan/PHEA-blended hydrogels were prepared from PHEA and chitosan in various blend ratios. The water contents of the hydrogels were in the range of 50%-80% (wt). The attachment and growth of fibroblast cells(L929) on the hydrogels were studied. The results indicated the PHEA content in hydrogels has great effect on cell attachment but has little effect on the growth of L929 cells.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biocompatible Materials / chemistry
Cell Adhesion / physiology
Cell Division / physiology
Cells, Cultured
Chitin / analogs & derivatives
Chitin / chemistry*
Chitosan
Fibroblasts / cytology*
Fibroblasts / physiology
Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry*
Mice
Peptides / chemistry*
Water / chemistry

Substances

Biocompatible Materials
Peptides
alpha,beta-poly((2-hydroxyethyl)-aspartamide)
Water
Chitin
Hydrogel, Polyethylene Glycol Dimethacrylate
Chitosan