Monoboronic acid sensor that displays anomalous fluorescence sensitivity to glucose

Org Lett. 2002 May 2;4(9):1503-5. doi: 10.1021/ol025723x.

Abstract

[reaction: see text]. A monoboronic acid fluorescent sensor was conveniently synthesized from 3-nitronaphthalic anhydride and 3-aminophenylboronic acid. This novel saccharide probe exhibits dual emission suitable for ratiometric sensing and displays a remarkable sensitivity for glucose relative to fructose and galactose.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Boronic Acids / chemistry*
  • Carbohydrates / chemistry
  • Chelating Agents / chemistry
  • Fluorescence
  • Fluorescent Dyes / chemical synthesis*
  • Glucose / chemistry*
  • Hydrogen-Ion Concentration
  • Photochemistry
  • Spectrometry, Fluorescence

Substances

  • Boronic Acids
  • Carbohydrates
  • Chelating Agents
  • Fluorescent Dyes
  • Glucose