A new approach to the reduction of sulfoxides to sulfides with 1,3-dithiane in the presence of electrophilic bromine as catalyst

Nasser Iranpoor; Habib Firouzabadi; Hamid Reza Shaterian

doi:10.1021/jo016027y

A new approach to the reduction of sulfoxides to sulfides with 1,3-dithiane in the presence of electrophilic bromine as catalyst

J Org Chem. 2002 May 3;67(9):2826-30. doi: 10.1021/jo016027y.

Authors

Nasser Iranpoor¹, Habib Firouzabadi, Hamid Reza Shaterian

Affiliation

¹ Department of Chemistry, Shiraz University, Shiraz 71454, Iran. iranpoor@chem.susc.ac.ir

PMID: 11975533
DOI: 10.1021/jo016027y

Abstract

A new, mild, and novel method is described for the efficient deoxygenation of sulfoxides to their corresponding sulfides with 1,3-dithiane at room temperature in the presence of catalytic amounts of N-bromosuccinimide (NBS), 2,4,4,6-tetrabromo-2,5-cyclohexadienone (TABCO), or Br(2) as the source of electrophilic bromine.