Isolation and structures of guaianolides from Carpesium macrocephalum

Mi-Ran Kim; Chang-Soo Kim; Kyung-Hwa Hwang; Il-Yeong Park; Seoung-Soo Hong; Jong-Keun Son; Dong-Cheul Moon

doi:10.1021/np010388r

Isolation and structures of guaianolides from Carpesium macrocephalum

J Nat Prod. 2002 Apr;65(4):583-4. doi: 10.1021/np010388r.

Authors

Mi-Ran Kim¹, Chang-Soo Kim, Kyung-Hwa Hwang, Il-Yeong Park, Seoung-Soo Hong, Jong-Keun Son, Dong-Cheul Moon

Affiliation

¹ College of Pharmacy, Chungbuk National University, Cheongju 361-763, Korea.

PMID: 11975507
DOI: 10.1021/np010388r

Abstract

Two new guaianolides, 4alpha,10alpha-dihydroxy-1beta(H),5beta(H)-guai-11(13)-en-8alpha,12-olide (2) and 4beta,10beta-dihydroxy-5alpha(H)-1,11(13)-guaidien-8alpha,12-olide (3), from Carpesium macrocephalum were isolated, and their structures were elucidated on the basis of spectroscopic studies.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Asteraceae / chemistry*
Chromatography, High Pressure Liquid
Korea
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plants, Medicinal / chemistry*
Sesquiterpenes / chemistry
Sesquiterpenes / isolation & purification*
Spectrophotometry, Ultraviolet
Stereoisomerism

Substances

4alpha,10alpha-dihydroxy-1beta(H),5beta(H)-guai-11(13)-en-8alpha,12-olide
4beta,10beta-dihydroxy-5alpha(H)-1,11(13)-guaidien-8alpha,12-olide
Sesquiterpenes