Automatic P-wave analysis of patients prone to atrial fibrillation

Med Biol Eng Comput. 2002 Jan;40(1):63-71. doi: 10.1007/BF02347697.

Abstract

A method is presented for automatic analysis of the P-wave, based on lead II of a 12-lead standard ECG, in resting conditions during a routine examination for the detection of patients prone to atrial fibrillation (AF), one of the most prevalent arrhythmias. First, the P-wave was delineated, and this was achieved in two steps: the detection of the QRS complexes for ECG segmentation, using a wavelet analysis method, and a hidden Markov model to represent one beat of the signal for P-wave isolation. Then, a set of parameters to detect patients prone to AF was calculated from the P-wave. The detection efficiency was validated on an ECG database of 145 patients, including a control group of 63 people and a study group of 82 patients with documented AF. A discriminant analysis was applied, and the results obtained showed a specificity and a sensitivity between 65% and 70%.

MeSH terms

  • Adult
  • Aged
  • Atrial Fibrillation / diagnosis*
  • Electrocardiography / methods*
  • Female
  • Humans
  • Male
  • Markov Chains
  • Middle Aged
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted*