Abstract
In 2 patients infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy was unable to suppress HIV replication as a result of the emergence of drug-resistant HIV variants. Human cytomegalovirus (HCMV) retinitis developed in both patients, and an unusually complex mixture of drug-resistant HCMV variants was detected in both patients.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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AIDS-Related Opportunistic Infections / virology*
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Adult
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Antiretroviral Therapy, Highly Active
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Cytomegalovirus / drug effects*
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Cytomegalovirus / isolation & purification
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Cytomegalovirus Infections / etiology
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Cytomegalovirus Infections / virology
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Cytomegalovirus Retinitis / etiology
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Cytomegalovirus Retinitis / virology*
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Drug Resistance, Multiple*
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HIV / drug effects
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HIV Infections / complications*
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HIV Infections / drug therapy
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Humans
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Male
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Virus Replication / drug effects