Structure determination of a new lupane-type triterpene, tiarellic acid, isolated from Tiarella polyphylla

Si-Hyung Park; Sei-Ryang Oh; Kyung-Seop Ahn; Jae-Gil Kim; Hyeong-Kyu Lee

doi:10.1007/BF02975262

Structure determination of a new lupane-type triterpene, tiarellic acid, isolated from Tiarella polyphylla

Arch Pharm Res. 2002 Feb;25(1):57-60. doi: 10.1007/BF02975262.

Authors

Si-Hyung Park¹, Sei-Ryang Oh, Kyung-Seop Ahn, Jae-Gil Kim, Hyeong-Kyu Lee

Affiliation

¹ Department of Medicinal Plant Resources, Mokpo National University, Jeonnam, Korea.

PMID: 11885693
DOI: 10.1007/BF02975262

Abstract

A new 27-carboxylic lupane-type triterpene, tiarellic acid (1), was isolated from Tiarella polyphylla together with corosolic acid (2) and tormentic acid (3). Tiarellic acid was characterized as 3,23-dihydroxy-20(29)-lupen-27-oic acid and its NMR data were unambiguously assigned using 2-D NMR techniques.

MeSH terms

Antineoplastic Agents, Phytogenic / chemistry
Korea
Magnetic Resonance Spectroscopy
Molecular Conformation
Plants, Medicinal / chemistry*
Spectrometry, Mass, Electrospray Ionization
Spectrophotometry, Infrared
Triterpenes / chemistry*
Triterpenes / isolation & purification

Substances

Antineoplastic Agents, Phytogenic
Triterpenes
tiarellic acid
euscaphic acid
corosolic acid