Critical illness as a model of hypothalamic ageing

Greet Van den Berghe; Stephen M Shalet

Critical illness as a model of hypothalamic ageing

Novartis Found Symp. 2002:242:205-15; discussion 216-21.

Authors

Greet Van den Berghe¹, Stephen M Shalet

Affiliation

¹ Department of Intensive Care Medicine, University Hospital, Gasthuisberg, Catholic University of Leuven, Belgium.

PMID: 11855689

Abstract

In this review we shall consider the endocrine changes seen in the various hypothalamic pituitary-target gland axes at different stages of critical illness and conclude by comparing these changes with those seen in the normal ageing process.

Publication types

Review

MeSH terms

Aging / metabolism*
Animals
Critical Illness*
Growth Hormone / metabolism
Humans
Hypothalamo-Hypophyseal System / metabolism*
Luteinizing Hormone / metabolism
Models, Biological
Pituitary-Adrenal System / metabolism*
Prolactin / metabolism
Testosterone / metabolism
Thyroid Gland / metabolism
Thyrotropin / metabolism

Substances

Testosterone
Prolactin
Luteinizing Hormone
Thyrotropin
Growth Hormone