Some problems in the detection of strong mutagen MX formed by chlorinating the aromatic acids and phenolic compounds

Lu Junhe; Zou Huixia; Yang Chengyong; Yu Zirui; Zhang Jinqi

doi:10.1016/s0043-1354(01)00290-1

Some problems in the detection of strong mutagen MX formed by chlorinating the aromatic acids and phenolic compounds

Water Res. 2002 Feb;36(4):970-4. doi: 10.1016/s0043-1354(01)00290-1.

Authors

Lu Junhe¹, Zou Huixia, Yang Chengyong, Yu Zirui, Zhang Jinqi

Affiliation

¹ State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, People's Republic of China.

PMID: 11848368
DOI: 10.1016/s0043-1354(01)00290-1

Abstract

Ten compounds with aromatic acid and phenolic structure were chlorinated at laboratory conditions and MX analysis by GC/MS at scan mode. None of these compounds produced MX, which is contrary to the results of other researchers. The whole procedure was investigated and it was found that the results obtained at scan mode was more reliable than at SIM mode because of the possible interference. The structural characteristic of the precursors of MX is proposed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acids, Aromatic / chemistry
Environmental Monitoring / methods*
Furans / analysis*
Gas Chromatography-Mass Spectrometry*
Mutagens / analysis*
Phenols / chemistry
Reproducibility of Results
Sensitivity and Specificity
Water Pollutants, Chemical / analysis*

Substances

Amino Acids, Aromatic
Furans
Mutagens
Phenols
Water Pollutants, Chemical
3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone