Transretinoic acid inhibits rats gastric epithelial dysplasia induced by N-methyl-N-nitro-N-nitrosoguanidine: influences on cell apoptosis and expression of its regulatory genes

World J Gastroenterol. 2001 Jun;7(3):394-8. doi: 10.3748/wjg.v7.i3.394.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Apoptosis / drug effects*
  • Caspase 1 / analysis
  • Caspase 1 / genetics
  • Cyclin D1 / analysis
  • Cyclin D1 / genetics
  • Gastric Mucosa / chemistry
  • Gastric Mucosa / pathology*
  • Gene Expression / drug effects
  • Immunohistochemistry
  • Male
  • Membrane Glycoproteins / analysis
  • Membrane Glycoproteins / genetics
  • Methylnitronitrosoguanidine
  • RNA, Messenger / analysis
  • Rats
  • Rats, Wistar
  • Stomach Diseases / chemically induced
  • Stomach Diseases / drug therapy*
  • Stomach Diseases / pathology*
  • Tretinoin / pharmacology*
  • fas Receptor / analysis
  • fas Receptor / genetics

Substances

  • Antineoplastic Agents
  • Membrane Glycoproteins
  • RNA, Messenger
  • fas Receptor
  • Methylnitronitrosoguanidine
  • Cyclin D1
  • Tretinoin
  • Caspase 1