Role of hematopoietic growth factors in angiogenesis

Acta Haematol. 2001;106(4):157-61. doi: 10.1159/000046611.

Abstract

In early ontogeny, hematopoiesis is closely associated with angiogenesis. This article reviews recent studies of the effect of hematopoietic growth factors on several endothelial cell functions together with recent findings about angiogenesis and antiangiogenic therapies in hematopoietic malignancies such as leukemia, lymphoma and myeloma.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Endothelium, Vascular / metabolism
  • Endothelium, Vascular / physiology
  • Hematologic Neoplasms / drug therapy
  • Hematologic Neoplasms / metabolism
  • Hematologic Neoplasms / pathology
  • Hematopoiesis / immunology
  • Hematopoiesis / physiology
  • Hematopoietic Cell Growth Factors / metabolism
  • Hematopoietic Cell Growth Factors / physiology*
  • Humans
  • Neovascularization, Pathologic / drug therapy
  • Neovascularization, Pathologic / physiopathology
  • Neovascularization, Pathologic / prevention & control
  • Neovascularization, Physiologic / drug effects
  • Neovascularization, Physiologic / physiology*

Substances

  • Hematopoietic Cell Growth Factors