Course of shock in rats with different resistance to shockogenic trauma during Crush syndrome

Bull Exp Biol Med. 2001 Oct;132(4):946-9. doi: 10.1023/a:1013654925156.

Abstract

Experiments on narcotized rats with crush syndrome showed that low resistant animals developed pronounced hypovolemia, hemoconcentration, blood hyperviscosity, impairment of oxygen metabolism, and central and peripheral hemodynamic disturbances, whereas in highly resistant rats the hemodynamics and oxygen supply to tissues were maintained at a sufficient level, while hemoconcentration and the increase in blood viscosity were less pronounced.

MeSH terms

  • Animals
  • Crush Syndrome*
  • Dose-Response Relationship, Drug
  • Hemodynamics
  • Hypovolemia
  • Male
  • Oxygen / metabolism
  • Rats
  • Shock*

Substances

  • Oxygen